PhD Student Position in HBV and Liver Fibrosis Research

"Knowledge becomes health" - we are filling this motto with life every day, developing new ideas and improv-ing old-established knowledge. The University Hospital Frankfurt has existed since 1914. Our around 8,500 employees contribute with their skills and knowledge to the 33 specialist clinics, theoretical clinical institutes, and administrative departments. The close connection of health care with research and teaching, as well as a climate of collegiality, internationality, and cross-professional cooperation characterize the university hospital. The Department of Gastroenterology and Hepatology at Goethe University Hospital Frankfurt offers comprehensive diagnostic and therapeutic services for liver and digestive diseases. The research group led by Dr. Görgülü, Clinician Scientist, is part of the DFG-funded INDEEP program and focuses on understanding the impact of Hepatitis B Virus (HBV) mutations on liver fibrosis and inflammatory processes. Our lab operates within an innovative research environment and is embedded in a strong collaborative network that includes both national and international partners. We are supported by grants from the German Research Foundation (DFG) and Goethe University, allowing us to conduct cutting-edge translational research. Our team employs state-of-the-art technologies, including multiplex fluorescent-bead assays, phosphoblotting, and co-culture systems with human immune cells, to analyze the role of HBV in cellular signaling pathways, immune responses, and fibrosis development. Specifically, we investigate kinase signaling pathways, cytokine profiles, and receptor expression patterns, aiming to uncover new insights into HBV-induced liver pathology and to explore potential therapeutic targets. We are seeking a highly motivated PhD student to join our team. This position offers an exceptional opportunity to work on a clinically relevant project with direct implications for the management of chronic HBV infections.